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PT & aPTT Reagents: What Indian Labs Must Know Before Buying Them

Introduction: Choosing Coagulation Reagents is Not Just About Price!

Every clinical lab in India performing PT or aPTT tests depends heavily on reagents and unfortunately, most labs still select reagents based on cost alone without evaluating other critical factors — often resulting in poor reporting quality, repeat tests, and wastage.

This Blog explains what Indian labs must know before buying PT & aPTT reagents.

1. Understand ISI Value for PT Reagents

• Lower ISI (International Sensitivity Index) closer to 1.0 = Better accuracy
• WHO recommends ISI between 0.95 to 1.1 for optimal INR reporting

QuikCoag PT Reagents  offered by Operon Biotech have low ISI range for precise results.

2. Choose Right Pack Size as per Sample Load

• Small Labs (1-5 samples/day) → Prefer liquid stable PT/aPTT reagents
• Mid to High Volume Labs → Use lyophilized PT reagent packs for cost efficiency

Tip: Smaller reagent packs can reduce wastage.

3. Always Use Manufacturer Recommended Calcium Chloride

• Especially important for aPTT testing
• Molarity of CaCl2 directly impacts clot formation timing

Operon Biotech provides validated CaCl2 for consistent aPTT results.

4. Ensure Proper Storage & Handling

• PT/aPTT reagents need cold chain maintenance (2-8°C)
• Exposure to higher temperature = Shorter shelf life

Choose a vendor who guides labs on storage practices.

5. Prefer Reagents with QC & Validation Support

• Good suppliers provide Internal QC samples
• Validation reports with recommended settings

Operon Biotech offers end-to-end QC guidance for QuikCoag reagents.

6. Avoid Reagent Brands that are Not Dedicated for Coagulation

Many IVD companies just add PT/aPTT reagents to augment their large portfolio without in-depth expertise.

Choose vendors specialized in coagulation — like Operon Biotech working exclusively in haemostasis segment with decades of expertise.

Conclusion: Reagent Selection is Strategy, Not Purchase

Right PT & aPTT reagents improve lab credibility, reporting accuracy, and reduce repeat tests.

Explore QuikCoag® range by Operon Biotech:

• US FDA and CE certified
• Market tested in Indian labs.

Visit: www.operonbiotech.com to know more or reach us at info@operonbiotech.com